Enthusiasm instead of simple satisfaction

The first Osteology Research Academy in person meeting took place this year in Boston from 4-7 October 2021 under the leadership of chairmen William Giannobile, David Kim and Myron Nevins (all USA). 16 US top speakers gave lectures on research design and methodology. The 41 participants of this fully booked event were able to gain a comprehensive view on most aspects of pre-clinical and clinical studies.

Following the path of experience

The three chairmen opened the event with presentations on the various development and research steps of new technologies, from clinical trials to clinical practice, as well as an overview of biologics for bone regeneration. Maria Troulis then presented on principles of oral and maxillofacial reconstruction, where she showed different minimally invasive surgical techniques and explained how she developed them over the years. Her lecture was followed by a very interesting presentation of Kenneth Kornman on precision medicine in dentistry. He showed among other things that chronic inflammatory diseases have multiple different paths and that patients with periodontitis hence respond individually to standard treatment. Therefore, the new periodontitis classification is based on multiple paths and Kornman predicts that the future of periodontitis therapy will be based on biomarkers.

Knowledge transfer from the best

Another remarkable talk was David Mooney’s, himself an engineer whose publications have been numerously cited. He spoke about the undervalued role of biomaterial stiffness on the regenerative capacity of stem cells, with most current studies ignoring that tissues are typically viscoelastic. He demonstrates that viscoelasticity impacts spreading, proliferation and fate of stem cells, and this work has inspired new medical adhesives whose physical properties can control the regenerative processes. A very interactive session was subsequently led by Jill Helms who presented a current, integrated, multiscale understanding of the biology and mechanics of dental implant osseointegration. Participants got a deeper appreciation of the underlying regenerative potential of different bone types and gained insights into ways to preserve bone viability during implant site preparation. Hom-Lay Wang later on lectured on research methods for guided tissue and bone regeneration, familiarizing the participants with the “PASS” principles (primary wound closure, angiogenesis, space and stability) for achieving predictable tissue and bone regeneration. Cathie Spino gave a very vivid presentation about statistical principles for studies in oral health and involved participants both in the theoretical as well as the practical part of her topic.

David Mooney in Action

To be continued for sure

The participants left the three-and-a-half-day intensive course full of enthusiasm about the experience of classroom sessions with leading experts, case studies and exercises in teams. The casual atmosphere encouraged each and every one to go back home and implement the newly acquired knowledge in their own clinical research projects. Chairman William Giannobile concluded that this Osteology Research Academy had exceeded the very high standards set and that it had certainly not been the last of its kind.

Group photo