Osteology Grant Publications

To date, 48 projects funded by the Osteology Foundation resulted in 68 publications in the following peer-reviewed journals:


  • Farina R, Franceschetti G, Travaglini D, Consolo U, Minenna L, Schincaglia GP, Riccardi O, Bandieri A, Maietti E, Trombelli L. "Morbidity Following Transcrestal and Lateral Sinus Floor Elevation: A Randomized Trial." J Clin Periodontol 2018. Abstract
  • Cha JK, Sanz M, Jung UW. "Human Autopsy Study of Peri-Implant Dehiscence Defects with Guided Bone Regeneration: A Case Report." Int J Periodontics Restorative Dent 2018. Abstract
  • Cha JK, Sun YK, Kim MJ, Sanz M, Jung UW. "Anti‐Resorptive Effect of Pamidronate on Extraction Socket Wall in Dogs." Clin Oral Implants Res 2018, 0 (0), 1-9. Abstract
  • Cai X, Yang F, Walboomers XF, Wang Y, Jansen JA, van den Beucken J, Plachokova AS. "Periodontal Regeneration Via Chemoattractive Constructs." J Clin Periodontol 2018, 45 (7), 851-860. Full Text
  • Calciolari E, Ravanetti F, Strange A, Mardas N, Bozec L, Cacchioli A, Kostomitsopoulos N, Donos N. "Degradation Pattern of a Porcine Collagen Membrane in an in Vivo Model of Guided Bone Regeneration." J Periodontal Res 2018, 53 (3), 430-439. Abstract
  • Urban I, Traxler H, Romero-Bustillos M, Farkasdi S, Bartee B, Baksa G, Avila-Ortiz G. "Effectiveness of Two Different Lingual Flap Advancing Techniques for Vertical Bone Augmentation in the Posterior Mandible: A Comparative, Split-Mouth Cadaver Study." Int J Periodontics Restorative Dent 2018, 38 (1), 35-40. Abstract
  • Nuñez J, Sanchez N, Vignoletti F, Sanz-Martin I, Caffesse R, Santamaria S, Garcia-Sanz JA, Sanz M. "Cell Therapy with Allogenic Canine Periodontal Ligament-Derived Cells in Periodontal Regeneration of Critical Size Defects." J Clin Periodontol 2018, 45 (4), 453-461. Abstract


  • Okada E, Nakata H, Yamamoto M, Kasugai S, Kuroda S. "Indirect Osteoblast Differentiation by Liposomal Clodronate." J Cell Mol Med 2017. Full Text
  • Jacobs C, Schramm S, Dirks I, Walter C, Pabst A, Meila D, Jacobs C, Wehrbein H. "Mechanical Loading Increases Pro-Inflammatory Effects of Nitrogen-Containing Bisphosphonate in Human Periodontal Fibroblasts." Clin Oral Investig 2017. Abstract
  • Elgali I, Omar O, Dahlin C, Thomsen P. "Guided Bone Regeneration: Materials and Biological Mechanisms Revisited." Eur J Oral Sci 2017, 125 (5), 315-337. Full Text
  • Omar O, Dahlin A, Gasser A, Dahlin C. "Tissue Dynamics and Regenerative Outcome in Two Resorbable Non-Cross-Linked Collagen Membranes for Guided Bone Regeneration: A Preclinical Molecular and Histological Study In vivo." Clin Oral Implants Res 2017, 1-13. Abstract
  • Hospodiuk M, Dey M, Sosnoski D, Ozbolat IT. "The Bioink: A Comprehensive Review on Bioprintable Materials." Biotechnol Adv 2017, 35 (2), 217-239. Abstract
  • Leberfinger AN, Ravnic DJ, Dhawan A, Ozbolat IT. "Concise Review: Bioprinting of Stem Cells for Transplantable Tissue Fabrication." Stem Cells Transl Med 2017, 6 (10), 1940-1948. Full Text
  • Ravnic DJ, Leberfinger AN, Koduru SV, Hospodiuk M, Moncal KK, Datta P, Dey M, Rizk E, Ozbolat IT. "Transplantation of Bioprinted Tissues and Organs: Technical and Clinical Challenges and Future Perspectives." Ann Surg 2017, 266 (1), 48-58. Abstract
  • Ozbolat IT, Moncal KK, Gudapati H. "Evaluation of Bioprinter Technologies." Additive Manufacturing 2017, 13, 179-200. Abstract
  • Mah W, Jiang G, Olver D, Gallant-Behm C, Wiebe C, Hart DA, Koivisto L, Larjava H, Häkkinen L. "Elevated Cd26 Expression by Skin Fibroblasts Distinguishes a Profibrotic Phenotype Involved in Scar Formation Compared to Gingival Fibroblasts." Am J Pathol 2017, 187 (8), 1717-1735. Abstract
  • Buffoli B, Favero G, Borsani E, Boninsegna R, Sancassani G, Labanca M, Rezzani R, Albanese M, Nocini PF, Rodella LF. "Sodium-DNA for Bone Tissue Regeneration: An Experimental Study in Rat Calvaria." Biomed Res Int 2017, Article in Press. Full Text
  • Chen Z, Bachhuka A, Han S, Wei F, Lu S, Visalakshan RM, Vasilev K, Xiao Y. "Tuning Chemistry and Topography of Nanoengineered Surfaces to Manipulate Immune Response for Bone Regeneration Applications." ACS Nano 2017, 11 (5), 4494-4506. Abstract
  • Han S, Chen Z, Han P, Hu Q, Xiao Y. "Activation of Macrophages by Lipopolysaccharide for Assessing the Immunomodulatory Property of Biomaterials". Tissue Eng Part A 2017. Abstract
  • Liu XL, Rao NJ, Huo L, Hu X, Lu WW, Zheng LW. "The Influence of Locally Applied Granulocyte-Colony Stimulating Factor on Osteoporotic Bone." Clin Oral Implants Res 2017, 28 (5), 586-593. Abstract
  • Pourgonabadi S, Müller H-D, Mendes JR, Gruber R. "Saliva Initiates the Formation of Pro-Inflammatory Macrophages in Vitro." Arch Oral Biol 2017, 73, 295-301. Abstract
  • Santamaría S, Sanchez N, Sanz M, Garcia-Sanz JA. "Comparison of Periodontal Ligament and Gingiva-Derived Mesenchymal Stem Cells for Regenerative Therapies." Clin Oral Investig 2017, 21 (4), 1095-1102. Abstract
  • Voss PJ, Matsumoto A, Alvarado E, Schmelzeisen R, Duttenhöfer F, Poxleitner P. "Treatment of Stage II Medication-Related Osteonecrosis of the Jaw with Necrosectomy and Autologous Bone Marrow Mesenchymal Stem Cells." Odontology 2017. Abstract


  • Todorov A, Kreutz M, Haumer A, Scotti C, Barbero A, Bourgine PE, Scherberich A, Jaquiery C, Martin I. "Fat-Derived Stromal Vascular Fraction Cells Enhance the Bone-Forming Capacity of Devitalized Engineered Hypertrophic Cartilage Matrix." Stem Cells Transl Med 2016, 5 (12), 1684-1694. Full Text
  • Andalib MN, Dzenis Y, Donahue HJ, Lim JY. "Biomimetic Substrate Control of Cellular Mechanotransduction." Biomater Res 2016, 20 (1), 11. Full Text
  • Andalib MN, Lee JS, Ha L, Dzenis Y, Lim JY. "Focal Adhesion Kinase Regulation in Stem Cell Alignment and Spreading on Nanofibers." Biochem Biophys Res Commun 2016, 473 (4), 920-925. Full Text
  • Farina R, Zaetta A, Minenna L, Trombelli L. "Orbital and Periorbital Emphysema Following Maxillary Sinus Floor Elevation: A Case Report and Literature Review." J Oral Maxillofac Surg 2016, 74 (11), 2192.e1-2192.e7. Abstract
  • Fretwurst T, Grunert S, Woelber JP, Nelson K, Semper-Hogg W. "Vitamin D Deficiency in Early Implant Failure: Two Case Reports." Int J Implant Dent 2016, 2 (1), 24. Full Text
  • Gomez-Florit M, Pacha-Olivenza MA, Fernández-Calderón MC, Córdoba A, González-Martín ML, Monjo M, Ramis JM. "Quercitrin-Nanocoated Titanium Surfaces Favour Gingival Cells against Oral Bacteria." Sci Rep 2016, 6, 22444. Full Text
  • Liu XL, Hu X, Cai WX, Lu WW, Zheng LW. "Effect of Granulocyte-Colony Stimulating Factor on Endothelial Cells and Osteoblasts." Biomed Res Int 2016, 2016, 8. Full Text
  • Schmitt CM, Moest T, Lutz R, Wehrhan F, Neukam FW, Schlegel KA. "Long-Term Outcomes after Vestibuloplasty with a Porcine Collagen Matrix (Mucograft®) Versus the Free Gingival Graft: A Comparative Prospective Clinical Trial." Clin Oral Implants Res 2016, 27 (11), e125-e133. Abstract


  • Hao J, Chou J, Kuroda S, Otsuka M, Kasugai S, Lang NP. "Strontium Hydroxyapatite in Situ Gel-Forming System – a New Approach for Minimally Invasive Bone Augmentation." Clin Oral Implants Res 2015, 26 (5), 581-585. Abstract
  • Carvajal Monroy PL, Grefte S, Kuijpers-Jagtman AM, Helmich MPAC, Wagener FADTG, Von den Hoff JW. "Fibrosis Impairs the Formation of New Myofibers in the Soft Palate after Injury." Wound Repair Regen 2015, 23 (6), 866-873. Abstract
  • Elangovan S, Khorsand B, Do A-V, Hong L, Dewerth A, Kormann M, Ross RD, Rick Sumner D, Allamargot C, Salem AK. "Chemically Modified Rna Activated Matrices Enhance Bone Regeneration." J Control Release 2015, 218, 22-28. Full Text
  • Hamid O, Pensch M, Agis H. "Release Kinetics of Prolyl Hydroxylase Inhibitors from Collagen Barrier Membranes." J Biomater Appl 2015, 29 (8), 1059-1067. Abstract
  • Hillary S, Hamel FG, Jeong Soon L, Ligyeom H, Jung Yul L. "Mechanical Control of Mesenchymal Stem Cell Adipogenesis." Endocrinol Metab Synd 2015, 4 (152). Full Text
  • Koo AN, Ohe J-Y, Lee D-W, Chun J, Lee HJ, Kwon Y-D, Lee SC. "Bone-Regenerative Activity of Parathyroid Hormone-Releasing Nano-Hydroxyapatite/Poly(L-Lactic Acid) Hybrid Scaffolds." Macromol Res 2015, 23 (12), 1168-1173. Abstract
  • Kuchler U, Keibl C, Fügl A, Schwarze UY, Tangl S, Agis H, Gruber R. "Dimethyloxalylglycine Lyophilized onto Bone Substitutes Increase Vessel Area in Rat Calvarial Defects." Clin Oral Implants Res 2015, 26 (5), 485-491. Abstract
  • Liu XL, Li CL, Lu WW, Cai WX, Zheng LW. "Skeletal Site-Specific Response to Ovariectomy in a Rat Model: Change in Bone Density and Microarchitecture." Clin Oral Implants Res 2015, 26 (4), 392-398. Abstract
  • Riehl BD, Lee JS, Ha L, Lim JY. "Fluid-Flow-Induced Mesenchymal Stem Cell Migration: Role of Focal Adhesion Kinase and Rhoa Kinase Sensors." J R Soc Interface 2015, 12 (104). Full Text
  • Thoma DS, Nänni N, Benic GI, Weber FE, Hämmerle CHF, Jung RE. "Effect of Platelet-Derived Growth Factor-Bb on Tissue Integration of Cross-Linked and Non-Cross-Linked Collagen Matrices in a Rat Ectopic Model." Clin Oral Implants Res 2015, 26 (3), 263-270. Abstract
  • Trimmel K, Cvikl B, Müller HD, Nürnberger S, Gruber R, Moritz A, Agis H. "L-Mimosine Increases the Production of Vascular Endothelial Growth Factor in Human Tooth Slice Organ Culture Model." Int Endod J 2015, 48 (3), 252-260. Abstract


  • Agis H, Hueber L, Pour Sadeghian N, Pensch M, Gruber R. "In Vitro Release of Dimethyloxaloylglycine and L-Mimosine from Bovine Bone Mineral." Arch Oral Biol 2014, 59 (10), 1024-1031. Abstract
  • Jin Q, Giannobile WV. "Sdf-1 Enhances Wound Healing of Critical-Sized Calvarial Defects Beyond Self-Repair Capacity." PLoS One 2014, 9 (5), e97035. Full Text
  • Möller B, Wiltfang J, Acil Y, Gierloff M, Lippross S, Terheyden H. "Prevention of the Surface Resorption of Bone Grafts by Topical Application of Bisphosphonate on Different Carrier Materials." Clin Oral Investig 2014, 18 (9), 2203-2211. Abstract
  • Paradas-Lara I, Casado-Gómez I, Martín C, Martínez-Sanz E, López-Gordillo Y, González P, Rodríguez-Bobada C, Chamorro M, Arias P, Maldonado E, Ortega R, Berenguer B, Martínez-Álvarez C. "Maxillary Growth in a Congenital Cleft Palate Canine Model for Surgical Research." Journal of Cranio-Maxillofacial Surgery 2014, 42 (1), 13-21. Abstract
  • Schwarz F, Mihatovic I, Golubovic V, Becker J, Sager M. "Immunohistochemical Characteristics of Regenerated Bone after Surgical Therapy of Advanced Ligature-Induced Peri-Implantitis Defects." Clin Oral Investig 2014, 18 (6), 1679-1686. Abstract
  • Schwarz F, Mihatovic I, Shirakata Y, Becker J, Bosshardt D, Sculean A. "Treatment of Soft Tissue Recessions at Titanium Implants Using a Resorbable Collagen Matrix: A Pilot Study." Clin Oral Implants Res 2014, 25 (1), 110-115. Abstract


  • Kämmerer PW, Palarie V, Schiegnitz E, Nacu V, Draenert FG, Al-Nawas B. "Influence of a Collagen Membrane and Recombinant Platelet-Derived Growth Factor on Vertical Bone Augmentation in Implant-Fixed Deproteinized Bovine Bone – Animal Pilot Study." Clin Oral Implants Res 2013, 24 (11), 1222-1230. Abstract
  • Martínez-Álvarez C, González-Meli B, Berenguer-Froehner B, Paradas-Lara I, López-Gordillo Y, Rodríguez-Bobada C, González P, Chamorro M, Arias P, Hilborn J, Casado-Gómez I, Martínez-Sanz E. "Injection and Adhesion Palatoplasty: A Preliminary Study in a Canine Model." J Surg Res 2013, 183 (2), 654-662. Abstract
  • Schmitt C, Lutz R, Doering H, Lell M, Ratky J, Schlegel KA. "Bio-Oss® Blocks Combined with Bmp-2 and Vegf for the Regeneration of Bony Defects and Vertical Augmentation." Clin Oral Implants Res 2013, 24 (4), 450-460. Abstract
  • Schmitt CM, Tudor C, Kiener K, Wehrhan F, Schmitt J, Eitner S, Agaimy A, Schlegel KA. "Vestibuloplasty: Porcine Collagen Matrix Versus Free Gingival Graft: A Clinical and Histologic Study." J Periodontol 2013, 84 (7), 914-923. Abstract


  • Dvorak G, Fügl A, Watzek G, Tangl S, Pokorny P, Gruber R. "Impact of Dietary Vitamin D on Osseointegration in the Ovariectomized Rat." Clin Oral Implants Res 2012, 23 (11), 1308-1313. Abstract
  • Oortgiesen DAW, Plachokova AS, Geenen C, Meijer GJ, Walboomers XF, van den Beucken JJJP, Jansen JA. "Alkaline Phosphatase Immobilization onto Bio-Gide® and Bio-Oss® for Periodontal and Bone Regeneration." J Clin Periodontol 2012, 39 (6), 546-555. Abstract


  • Cordaro L, Torsello F, Morcavallo S, di Torresanto VM. "Effect of Bovine Bone and Collagen Membranes on Healing of Mandibular Bone Blocks: A Prospective Randomized Controlled Study." Clin Oral Implants Res 2011, 22 (10), 1145-1150. Abstract
  • Fuegl A, Tangl S, Keibl C, Watzek G, Redl H, Gruber R. "The Impact of Ovariectomy and Hyperglycemia on Graft Consolidation in Rat Calvaria." Clin Oral Implants Res 2011, 22 (5), 524-529. Abstract
  • Kuchler U, Luvizuto ER, Tangl S, Watzek G, Gruber R. "Short-Term Teriparatide Delivery and Osseointegration: A Clinical Feasibility Study." J Dent Res 2011, 90 (8), 1001-1006. Abstract
  • Schwarz F, Sahm N, Mihatovic I, Golubovic V, Becker J. "Surgical Therapy of Advanced Ligature-Induced Peri-Implantitis Defects: Cone-Beam Computed Tomographic and Histological Analysis." J Clin Periodontol 2011, 38 (10), 939-949. Abstract
  • Wu G, Hunziker EB, Zheng Y, Wismeijer D, Liu Y. "Functionalization of Deproteinized Bovine Bone with a Coating-Incorporated Depot of Bmp-2 Renders the Material Efficiently Osteoinductive and Suppresses Foreign-Body Reactivity." Bone 2011, 49 (6), 1323-1330. Abstract


  • Amerio P, Vianale G, Reale M, Muraro R, Tulli A, Piattelli A. "The Effect of Deproteinized Bovine Bone on Osteoblast Growth Factors and Proinflammatory Cytokine Production." Clin Oral Implants Res 2010, 21 (6), 650-655. Abstract
  • Artzi Z, Nemcovsky CE, Tal H, Weinberg E, Weinreb M, Prasad H, Rohrer MD, Kozlovsky A. "Simultaneous Versus Two-Stage Implant Placement and Guided Bone Regeneration in the Canine: Histomorphometry at 8 and 16 Months." J Clin Periodontol 2010, 37 (11), 1029-1038. Abstract
  • Davies LC, Locke M, Webb RDJ, Roberts JT, Langley M, Thomas DW, Archer CW, Stephens P. "A Multipotent Neural Crest-Derived Progenitor Cell Population Is Resident within the Oral Mucosa Lamina Propria." Stem Cells Dev 2010, 19 (6), 819-830. Abstract
  • Knabe C, Berger G, Gildenhaar R, Ducheyne P, Stiller M. "Novel, Rapidly Resorbable Bioceramic Bone Grafts Produce a Major Osteogenic Effect - the Pre-Clinical Evidence." Adv Sci Tech 2010, 76, 214-223. Abstract
  • Trubiani O, Fulle S, Traini T, Paludi M, la Rovere R, Orciani M, Caputi S, Piattelli A. "Functional Assay, Expression of Growth Factors and Proteins Modulating Bone-Arrangement in Human Osteoblasts Seeded on an Anorganic Bovine Bone Biomaterial." Eur Cell Mater 2010, 20, 72-83. Abstract


  • Perrotti V, Nicholls BM, Horton MA, Piattelli A. "Human Osteoclast Formation and Activity on a Xenogenous Bone Mineral." J Biomed Mater Res A 2009, 90A (1), 238-246. Abstract
  • Schwarz F, Ferrari D, Sager M, Herten M, Hartig B, Becker J. "Guided Bone Regeneration Using Rhgdf-5- and Rhbmp-2-Coated Natural Bone Mineral in Rat Calvarial Defects." Clin Oral Implants Res 2009, 20 (11), 1219-1230. Abstract
  • Schwarz F, Sahm N, Bieling K, Becker J. "Surgical Regenerative Treatment of Peri-Implantitis Lesions Using a Nanocrystalline Hydroxyapatite or a Natural Bone Mineral in Combination with a Collagen Membrane: A Four-Year Clinical Follow-up Report." J Clin Periodontol 2009, 36 (9), 807-814. Abstract


  • Schwarz F, Rothamel D, Herten M, Wüstefeld M, Sager M, Ferrari D, Becker J. "Immunohistochemical Characterization of Guided Bone Regeneration at a Dehiscence-Type Defect Using Different Barrier Membranes: An Experimental Study in Dogs." Clin Oral Implants Res 2008, 19 (4), 402-415. Abstract